Hi Jos,
Adobe creative cloud desktop does support proxy auto config file however you may need to open outbound for below Adobe links on your firewall.
| Address | Ports | |
|---|---|---|
| ccmdls.adobe.com | 443 | |
| ims-na1.adobelogin.com | 80 | 443 |
| ims-prod06.adobelogin.com | 443 | |
| na1r.services.adobe.com | 80 | 443 |
| prod-rel-ffc-ccm.oobesaas.adobe.com | 443 | |
| prod-rel-ffc.oobesaas.adobe.com | 443 | |
| lm.licenses.adobe.com | 80 | 443 |
| ccmdl.adobe.com | 80 | |
| swupmf.adobe.com | 80 | |
| swupdl.adobe.com | 80 | |
| prod.acp.adobeoobe.com | 443 | |
| interaction.adobe.com | 443 |
Thanks,
Ashish