Hi,
If I understood correctly, you have created an installation package including creative cloud desktop app through creative cloud packager not AAMEE.
Adobe creative cloud doesn’t get uninstalled even if all the products and updates are removed from machine. But this will not cause any issues (or extra space) on installation of new package.
Its recommended that if the package is modified (adding more products or updates to existing package) and installed then it should be uninstalled via msi of modified package.
Thanks,
Ashish